Uma uzibuza ukuthi "Iyini i-Boswellia serrata?" Usendaweni efanele. Ku-phytotherapy, i- I-Boswellia serrata Kuboniswa ikakhulukazi ekwelapheni i-osteoarthritis kanye ne-pathologies yokuvuvukala (isibonelo, i-rheumatoid arthritis, isifo sikaCrohn, i-ulcerative colitis).
boswellia (Salai guggal) Isihlahla esiphakathi nendawo somndeni wakwaBurseraceae futhi sidabuka ezindaweni ezinamagquma eNdiya.
Iyini i-Bowsellia Serrata?
Igama Boswellia Yigama elaqanjwa isazi sezitshalo saseNgilandi uRoxburgh ohlotsheni lwezitshalo ezihlanganisa izinhlobo eziningi, ezinye zazo ezazidume kakhulu kusukela ezikhathini zasendulo, njengoba zinikeza izinhlaka ezinuka kamnandi ezaziwa ngokuthi impepho. URoxburgh waphila ngekhulu le-XNUMX.
I-genus Boswellia ingeyomndeni I-Burseraceae, okuhlanganisa izinhlobo ezingaba ngu-700 zezitshalo zezihlahla zasezindaweni ezishisayo. Zonke lezi zitshalo zinikezwe imisele eminingi enenhlaka, okuthi lapho, lapho umuntu esika esiqwini sohlobo oluthile lwezinhlobo zezilwane, kuphume inhlaka emhlophe emhlophe. Le jusi iqina kancane emoyeni futhi yakhe izicucu ezakha impepho u inhlaka.
Leli gama elithi (olibanum) lisuselwa kwelesi-Arabhu elithi "al-lubàn", okusho okumhlophe, futhi kukholakala ukuthi libhekisela ngokunembile ekubukekeni kwento ebisi ekhishwa emagxolweni alezi zihlahla. Ngenkathi igama elithi impepho lisuselwa kwelesiLatini sakudala elithi "incensum = lit-fiery", ngoba ezikhathini zasendulo yayivele isetshenziselwa ukuyishisa ukuze kuthuthwe isiko.
Ivelaphi?
Ngokwesiko elidumile, i-Boswellia oleoresin isetshenziswe amakhulu eminyaka kokubili njenge impepho enamakha emikhosini yenkolo njengomuthi. I-resin iqoqwa ngokusika isiqu bese ihlukaniswa ngokwezimpawu ze-organoleptic (isibonelo, ukunambitheka, umbala, usayizi, umumo). Abakhiqizi abahamba phambili emhlabeni be-Boswellia resin yizifunda zaseNdiya zase-Andhra Pradesh, eMadhya Pradesh, eGujarat, eChhattisgarh, naseJharkhand. Kepha nalawo asempumalanga ne-Afrika, ngasogwini loLwandle Olubomvu, eSomalia, e-Abyssinia nase-Ethiopia, eningizimu ye-Arabia, ikakhulukazi i-Oman ne-Yemen, kanye nasePakistan.
Yiziphi izinhlobo ezivelele ngezindawo zazo?
Izinhlobo ezibaluleke kakhulu ze-Bowsellia ziyi B.Carterii, B.bhaw-dajiana, B. papyrifera, B. sacral y I-Boswellia serrata. Eyokugcina esizokhuluma ngayo namuhla. Endaweni banamahlelo abo, phakathi kwawo sikhumbula igama likaLuban, e-Arabia naseBengal; iKundur ePheresiya; I-Payana e-Malabar ne-Guggal e-India, amagama avame ukubhekisela eqophelweni lempepho etholakala kuwo. Ukunotha kwama-resin kungase kube nokubaluleka okukhulu kwezomnotho ezinhlotsheni ezishiwo, ezingaba into yezitshalo ezithile zezolimo, emazweni athile ashisayo nasendaweni eshisayo, ngisho nangaphandle kwezindawo ezivela kuzo.
Impepho nezinye izinto ezinenhlaka
Impepho ingabuye ichazwe ngokuthi impepho emsulwa noma eyiqiniso, ukuyihlukanisa kwezinye izinto ezinenhlaka ebhalsamu ezikhathini zasendulo zazishiswa ngenjongo yesiko noma yenhlanzeko, njengemure, i-benzoin, igalbanum, i-styrax.
Ukusetshenziswa kwalezi zinsalela ezinephunga elimnandi ngenjongo yokwelapha, ukuthungula kwesibulali magciwane endaweni ezungezile, noma kumahlelo amaqaba endaweni yaseMedithera naseMesophothamiya kwakwaziwa kusukela ezikhathini zasendulo, kwaze kwaba uphawu lomnikelo kuzo zonke izinhlobo zemikhosi yokukhulekela okusetshenziselwa ukukhulekela. kanye nezinjongo ezingokwesiko, ezingcwele nezingokwenkolo, njengoba kusenjalo nanamuhla ezinkolweni zobuKristu nezamaGreki-Orthodox. Emithini yendabuko yama-Indian Ayurvedic, inhlaka yempepho, egama layo linguSalai Guggal, isetshenziselwa ukugula okuhlukahlukene, ngokusetshenziswa okubanzi okubanzi.
Sinjani isitshalo se-Bowsellia serrata?
I-resinous exudate etholwe kuyo I-Boswellia serrata (ama-synonyms B. glabrous y B. thurifera) yiyona okukholakala ukuthi inezinto eziningi zokwelapha, yingakho kuyisihloko salesi sihloko.
Isuka eNdiya nasePakistan, i I-Boswellia serrata Isihlahla esiphakathi nendawo esingavamisile ukweqa amamitha angu-4-6 ubude, sinomqhele obanzi kanye nesiqu esikhulu esinamagatsha amaningi, esinamagxolo anombala omlotha aphephuka abe yiphepha elincane.
Lolu hlobo luthanda inhlabathi enesithwathwa, kodwa lumelana kakhulu nesomiso nesithwathwa futhi lubekezelela izimo ezimbi kakhulu: luphinde lukhule emithambekeni enamatshe, elenga phezu kwemihosha, futhi lungatholakala kumamitha ayi-1200 ngaphezu kolwandle.
Amaqabunga ama-compounds amakhulu ayancibilika: isitshalo siyaphumula ngesikhathi esishisayo nesomile kakhulu, silahlekelwa amaqabunga futhi simise imisebenzi yaso ebalulekile, yingakho kuthiwa siya "estivation". Izimbali ezincane ezinokhilimu-ezimhlophe ezinephunga elimnandi ziqoqwe kuma-inflorescence aqoqwe abizwa ngokuthi ama-racemes; isithelo i-drupe encane engunxantathu equkethe imbewu emithathu emise okwenhliziyo.
Yini eyenza i-Bowsellia serrata ibaluleke kangaka kwezokwelapha?
Ingxenyana yerabha ye-exudate ilingana no-23%, iyancibilika emanzini futhi yakhiwe ikakhulukazi ngama-polysaccharides. Okuqukethwe kwe-resinous kufinyelela ku-55% futhi kwenziwa ingxube ye-boswellic acid. Amafutha akhiwe ngamafutha abalulekile. Zonke lezi zakhi ziyahlangana ukunikeza umuthi izici zawo zokwelapha, iphunga elimnandi eliwukhiphayo lapho ushiswa, kanye nezakhiwo zawo zokwelapha.
Ngokombono wamakhemikhali, i-oleoresin yakhiwe cishe I-50% ye-boswellic acid (β-boswellic acid, acetyl-β-boswellic acid, 11-keto-β-boswellic acid, acetyl-11-keto-β-boswellic acid), nxazonke 15% amafutha abalulekile kanye amanye ama-polysaccharides (i-arabinose, i-galactose, i-xylose). i-boswelic acid (ikakhulukazi i-acetyl-11-keto-β-boswellic acid) kukhona ama-5-lipoxygenase inhibitors anamandla. Ngokuvimbela i-enzyme 5-lipoxygenase, a umphumela onamandla wokulwa nokuvuvukala ngokunciphisa ukuhlanganiswa kwe-leukotrienes (izinto ezihilelekile ekuphenduleni kokuvuvukala kwesistimu ne-asthmatic).
Umsebenzi we-pharmacological we-Boswellia serrata ube yisihloko sezifundo eziningi zesayensi emashumini eminyaka amuva nje. Ukuhlolwa okuhlukahlukene kwemitholampilo kubonise ukuthi i-Boswellia serrata ifaneleka, ngaphezu kwakho konke, ekwelapheni izifo ezitholakala ngokuvuvuka njenge isifo samathambo, njengoba kuvimbela ukuwohloka kwe-glycosaminoglycans futhi lokhu kubonakala ngomphumela oqinile wendawo wokulwa nokuvuvukala.
U-Pang X et al. ubonise ukuthi i-acetyl-11-keto-β-boswellic acid ivimbela ukukhula kwe-endothelial futhi ingase ibe usizo ekwelapheni umdlavuza we-prostate.
Isifinyezo senqubo yokulwa nokuvuvukala
Ngokufingqa kafushane indlela yokwenza, i-Boswellia serrata kucatshangwa ukuthi isebenza ngokuvimbela i-enzyme eyodwa, lipoxygenase, ngaleyo ndlela kuvimbele ukuhlanganiswa kwe-leukotrienes, okungukuthi, abaxhumanisi bamakhemikhali ababangela inqubo yokuvuvukala, kokubili okunamandla nokungapheli ezinhlotsheni ezihlukahlukene zezifo ezivuthayo.
Ngaphezu kwalokho, kubonakala sengathi ama-boswellic acid avimbela ukuthuthela endaweni yokuvuvukala kohlobo oluthile lwamangqamuzana amhlophe egazi, akhiqiza i-elastase, i-enzyme. i-proteolytic, endaweni evuthayo.obhekene nokubhujiswa kwe-collagen, ngakho-ke izicubu ezihilelekile enqubweni yokuvuvukala; njengoba ingenayo i-elastase, ubuqotho be-collagen bugcinwa futhi ukuwohloka kwezakhiwo ezihlangene (i-cartilage, i-ligaments, i-tendon) igwenywa ngokuvimbela umhlaba wonke ukuwohloka kwamalungu.
Okunye ukusetshenziswa okusacutshungulwa
Nakuba kungekho zifundo zesayensi esezenziwe mayelana nokusetshenziswa kwesitshalo ezinqubweni ze-asthmatic, i I-Boswellia serrata kungaba ngcono i-bronchoconstriction. Ngaphezu kwalokho, lesi sitshalo somuthi sinamandla umsebenzi we-antipyretic ngaphandle kokubangela imiphumela elimaza i-gastro.
Njengamanje, isetshenziselwa ukuqashelwa kwayo izici ze-expectorant, ama-bronchodilators, i-diaphoretic, kodwa ngaphezu kwakho konke okulwa nokuvuvukala kanye ne-analgesic ezinkingeni ze-musculoskeletal kanye nokuvuvukala kwe-osteoarticular.
Ku-phytotherapy, ama-boswellic acid asetshenziselwa kokubili izifo ezivuthayo (isb, i-osteoarthritis, i-osteoarthritis, i-extra-articular rheumatism) nokunye izifo ze-autoimmune (isb, isifo samathambo).
Ku-dermatology, i-extracts ye-Boswellia serrata isetshenziswa njenge ukuphilisa, izihlanzi zesikhumba (umphumela we-antimicrobial) kanye ukunwebeka (i-elastase inhibition).
Ukusetshenziswa kwayo kunconywa njenge-adjuvant uma kwenzeka ukuvuvukala kwendawo, izinkinga amalunga awohlokayo, ukwehla kwamakhono emoto ekuseni, ubuhlungu bemisipha, i-rheumatism, i-osteoarthritis, ukuvuvukala kwezicubu ezithambile ezifana ne-tendonitis, i-myositis, i-fibromyalgia, hlisa futhi ikakhulukazi isifo samathambo, kokubili ukusetshenziswa kwangaphakathi njengesithako kumafutha okugcoba namakhilimu okufaka amalunga abuhlungu.
Inolaka kakhulu kunama-NSAID
Imininingwane eyenza ukusetshenziswa kwe-Boswellia serrata kuthakazelise ukuthi yiyoIsenzo sokulwa nokuvuvukala esibangelwa ama-boswellic acid asilimaza i-gastro, njengama-synthetic anti-inflammatory molecules (NSAIDs). Eqinisweni, ama-synthetic anti-inflammatories asebenza ngokuvimbela ukukhiqizwa kwe-prostaglandin, izinto ezibangela ubuhlungu nokuvuvukala. Kodwa, njengoba lezi zinto nazo zinomsebenzi omuhle, njengokukhishwa kwe-mucus esiswini esivikela i-mucosa yesisu, isenzo sokulwa nokuvuvukala sihambisana ne-gastrolesivity ephawulekayo (i-gastritis, isilonda), akunjalo nge-boswellic acids, abangasebenzi ekuhlanganiseni kwe-prostaglandin.
Akuyona yonke into u-Bowsellia Serrata anayo enhle...
Ngokombono we-toxicological, lesi sitshalo akufanele sisetshenziswe ngokuhambisana nezidakamizwa ezivimbela ukuhlanganiswa kwe-leukotrienes (isibonelo, i-montelukast, i-zafirlukast, njll.) njengoba ingakwazi ukuqinisa imiphumela yabo. Futhi njengazo zonke izitshalo noma imithi, i-Boswellia iphikisana nokukhulelwa nokuncelisa.