La quercetin ndeyeboka re polyphenolic zvinhu zvinonzi flavonoids.

Flavonoids yakawanikwa nemusayendisiti weHungary Albert Szent-Györgyi, akawana vhitamini C (akakunda mubairo weNobel wemishonga uye physiology muna 1937), akaona izvozvo. flavonoids ine synergistic mhedzisiro ine vhitamini C.

Quercetin inonzi polyphenolic molecule inogadzirwa nemetabolism yezvimwe zvirimwa zvakadai sebhiza chestnut, calendula, hawthorn, chamomile, St. John's wort uye ginkgo biloba, asiwo michero, miriwo, mashizha, mbeu uye zviyo.

Zvivakwa zvinonzi zvakaitwa antioxidants uye anticancer, pakati pevamwe.

Tingawanepi quercetin?

Quercetin inoparadzirwa zvakanyanya muumambo hwemiti: tinoiwana mumichero, masvuuriro nemarinds yemaapuro nehanyanisi, cocoa, michero mitsvuku uye broccoli. Manyuko akapfuma zvikuru izvibereko zvecitrus, mafuta omuorivhi, hanyanisi, waini tsvuku, tii yegirini, uye wort St.

Iyo quercetin iyo inowanzoshandiswa mune zvekudya zvinowedzera inotorwa kubva kumabuds e shopora japonica (chirimwa chemhuri Fabaceae – Legumes) inozivikanwawo se Japanese Robinia, Japanese acacia kana pagoda tree. Chimiro, cheAsia yakabva (China neKorea), inokura munzvimbo dzinodziya uye dzine mwero uye yakapararirawo munzvimbo dzine mamiriro ekunze anodziya eEurope.

Kubvira shopora japonica yakapfuma kwazvo mu quercetin, zvinokwanisika kuwana inotorwa yakachena. Quercetin ndiyo yakanyanya inoshandiswa kune metabolic uye kuzvimba kusagadzikana uye basa guru rinofungidzirwa pairi ndiro antioxidant.

Muchokwadi, inobatsira kuderedza kuumbwa kwemahara radicals uye pro-inflammatory zvinhu, zvichiratidza kuve yakakosha mubatsiri wehutano hwedu. Pamusoro pazvo, zvivakwa zvinonzi zvakaringana vasoactive sezvo inowedzera kushorwa kwecapillaries uye inogadzirisa kupenya kwavo.

Quercetin Migumisiro

Quercetin ine zvinotevera mabasa:

• anti-inflammatory,
• antiestrogenic,
• kuderedza kuumbwa kwe endometrial tissue,
• kuderera kukuru kwe systolic blood pressure muvarwere vemuganhu, kunyanya kana vakanyanya kuwandisa,
• antiatherosclerotic nekudziviswa kweLDL oxidation uye nemhedzisiro arterial endothelial kukuvara,
• cardio kudzivirira,
• antiviral,
• immunomodulator,
• anti allergic,
• gastroprotective.

Ko quercetin inotorwa sei?

Quercetin inonyudzwa mumatumbo uye metabolites yayo inogoverwa nechiropa kune akasiyana matishu emuviri. Muplasma inosunga kune albumin. The plasma peak inosvika anenge maawa manomwe mushure mekudya uye kubvisa hafu yeupenyu inenge maawa makumi maviri nemashanu. Kuvepo kwequercetin nemuromo hakuna chokwadi: chokwadi, zvinoita sekunge quercetin iri nani uye inofananidzwa inofananidzwa muura kana ikatorwa pamwe nemafuta akadai sepakati cheni triglycerides. Ndosaka zvakakosha kuti ma supplements ane lipid zvinhu uye kuti anotorwa mudumbu rakazara.

Tichifunga kuti zvidzidzo zvesainzi zvakaratidza kuti kudya kwakanyanya kweflavonoids kunoderedza njodzi yezvirwere zvemoyo uye kuti quercetin ndiyo inonyanya kuwanikwa mukudya kwedu, zvinokurudzirwa kushandisa michero nemiriwo zuva nezuva.

Kana chokwadi huwandu hwakakwana hwepolyphenols husina kutorwa kana kunyanya hutano mamiriro umo zvakakosha kuti uzvitore muhuwandu hwakawanda, kushandiswa kwezvikafu zvinowedzera zvinogona kushandiswa chero zvichinge zvine zvakamisikidzwa, titrated zvinyorwa zvine chekuita neabsorption vanokurudzira. iyo inofarira kufananidzwa.

Mukuwedzera, iyo yakanyanya kudyiwa yezuva nezuva inobvumidzwa neBazi rezvehutano ndeye 200 mg zuva nezuva asi, nekuda kwekushandiswa mune zvimwe zvigadzirwa zvezvinhu zvinokurudzira kubatwa kwayo, huwandu hwakaderera hunenge hwakakwana.

Ndeapi manyuko emusikirwo equercetin?

Quercetin ndeimwe yeakawanda akawandisa ekudya flavonoids, zvakanyanya zvekuti avhareji yemazuva ese ekudya kuburikidza neyakajairwa chikafu inofungidzirwa kunge ingangoita 25-50 milligrams.

Zvimwe zvezvokudya/zvikafu zvakakwirira muquercetin zvinosanganisira:

• capers (maererano nehuremu, ndicho chirimwa chine zvakanyanya, 234 mg pa100 g yemabuds akaomeswa),
• Buckwheat,
• machena / matsvuku mazambiringa
• waini tsvuku (chaizvoizvo, mumazambiringa, izvi zvinogadzirwa mumarudzi machena uye matsvuku, asi maererano newaini, inoiswa pamusoro pezvose muwaini tsvuku nekuda kwekushandura)
• Hanyanisi dzvuku,
• Green tea,
• blueberry,
• Apple,
• propolis,
• celery,
• radish,
• kabichi.
• maapuro,
• mazambiringa,
• kofi,
• michero,
• broccoli,
• citric michero,
• uye cherries.

Mazhinji eflavonoids mukudya anobva kuquercetin.

Iyo yakanyanya bioavailable quercetin uye saka zviri nani kufananidzwa ndeye ganda reapuro.

Usakanda mateko

Zvakakosha kuyeuka kuti muhanyanisi tsvuku iyo yakakwirira ye quercetin inowanikwa kwete chete muchikamu chiri pedyo nemudzi, chikamu chemuti nehupamhi hwepamusoro, asiwo mune zvindori zvekunze. Chiitiko ichi chakajairika muzvisikwa uye mutemo usingambofa wakakanganwika mukicheni, kunyanya kana isu tiine mhosva tichibvisa ma peels uye ekunze akaturikidzana emiriwo uye michero zviri nyore, tichikanganwa kuti zvinomiririra zvakanyanya kukosha zvinyorwa zvebioactive zvinhu.

El kudyiwa kwechikafu chine mafuta pamwe chete nezvinodyiwa zve quercetin zvinoita kunge zvinokwanisa kuwedzera kutora kwayo. inoshanda, iyo pachayo pachayo yakanyanya kuganhurirwa. Uyewo kuvapo kwemacarbohydrates, nekuda kwekukurudzira kwegastrointestinal motility uye kuvirisa zviitiko muura, zvinogona kuva nemigumisiro yakanaka munyaya iyi.

Ko quercetin inokanganisa sei immune system?

Ichi chinhu chine antiviral properties inotsigirwa nezvidzidzo zvakasiyana-siyana mumhando dzemhuka, asi zvinosuruvarisa kusvika nhasi hatizivi maitiro chaiwo uye chiito chechinhu ichi pane immune system.

Mukupedzisa, mamwe dzidziso anotenda kuti inogona chete kubatsira mune mamwe mamiriro e Kunyanya kushushikana mupfungwa.

Chii chinoshandiswa quercetin?

Pakati pezviratidzo iyo inonyanya kushandiswa ndeye anti-inflammatory uye antioxidant properties, izvo zvakatungamirira kushandiswa kwayo munzvimbo dzakawanda dzekurapa uye nezvinangwa zvakasiyana:

• kutsigira immune system,
• kuderedza kuzvimba,
• antitumor efficacy (pamwe nekudzivirira),
• kudzora shuga yeropa,
• kutsigira kwemitambo yemitambo
• kudzivirira zvirwere zvemwoyo.

Zviratidzo zviduku zvinosanganisira:

• arthritis,
• interstitial cystitis,
• prostatitis.

Quercetin yakadzidzwa mukutsvagisa kwekutanga (in vitro, kureva, mumachubhu ebvunzo kana muganhu mumhando dzemhuka) uye mumakiriniki madiki miedzo (muvanhu), asi nepo ma supplements agara achisimudzirwa kurapa kenza nezvimwe zvirwere zviripo iye zvino. humbowo husina kukwana hwemhando yakakwana kuratidza humbowo hunogona kuyerwa.

Sei uye nguva yekutora quercetin kana iwe uchidzidzira mitambo?

Quercetin supplementation inogona kutsigira zvishoma resistance exercise performance.

Ko quercetin ine antioxidant chiito?

Basa rakanaka rinokonzerwa ne antioxidant chiito chinobatsira kurwisa mahara radicals.

anti-inflammatory action

Maererano nezvimwe zvidzidzo, quercetin inogona kubatsira mukurwisana nekuputika, asi zvinosuruvarisa, kunyange munyaya iyi, uchapupu hushoma panguva ino.

Inogona kubatsira kune prostatitis here?

Mune zvimwe zvidzidzo, quercetin yakarwisa kuzvimba kweprostate.

Inogona kutsigira hurongwa hwemwoyo here?

Quercetin inogona kubatsira kune yakajairika BP uye ine zvimwe zvakanaka zvehutano hwemoyo.

Sei uye nguva yekutora quercetin?

Chiyero chinoratidzwa mune zvimwe zvidzidzo chinosiyana pakati pe100 ne1.000 mg pazuva.

Ndezvipi zvinopesana uye mhedzisiro yequercetin?

Zvichipa kushayikwa kwezvidzidzo, zvinokurudzirwa kuti usatora quercetin panguva yekuzvitakura uye lactation.

Nguva dzose inobatsira kubvunza chiremba wako usati watora quercetin kuti usarudze kurapa kwakakodzera. Chiyero chinokurudzirwa hachifaniri kudarika.

Hesperidin uye quercetin

La angare imwe flavonoid iyo inowanikwa kunyanya mu citrus. Inoratidzwa ne antioxidant mhedzisiro, vasoprotective zvimiro zvinonzi kwairi nekuda kwekuita kwayo pane collagen uye inobatana tishu, saka hazvishamisi kuwana zvekuwedzera pamusika zvinosanganisa iyo nequercetin.

Hesperidin, zvivakwa uye zvinobatsira

Hesperidin mushonga wepanyama inobatsira kune microcirculation uye nekukanganisika kune chekuita nemoyo. Hemorrhoids, varicose tsinga, asiwo high cholesterol inogona kubatsirwa zvikuru nayo.

Wa, mwaka wecitrus, majisi, vitamini C ... uye kufunga kuti pane chikamu chemuchero chatisingafungi, nokuti chine ganda, chinovava, chakapfuma mumafuta anokosha: the piel. Uye zviri chaizvo mugoko apo tsvaga Imwe yeanonyanya kushandiswa flavonoids pakati pe antioxidant supplements, hesperidin.

Hesperidin iripo muganda uye chena ganda rezasi peganda remichero yecitrus. Icho chinonyanya kufadza chikamu chehesperidin mumishonga yemishonga uye yemishonga munda ndeye muitironekuda kweiyo vasoprotective properties.

Nhoroondo ye Hesperidin Properties

Zvinhu zve hesperidin zvinoratidzwa mu microcirculation, mutsinga dzeropa uye mberi. Ngationei zvirinani zviitwa izvi flavonoid inoita:

• capillarotropic: tones the capillaries, inodzivirira kuwedzera kwavo uye inobatsira kusimbisa nekuvandudza capillary structure.
• vasoprotective: inoita toning uye inodzivirira chiito patsinga dzeropa, kudzivirira atony yavo, kukurudzira kutenderera kwevenous uye kuita anti-inflammatory action.
• hypocholesterolemic: inokwanisa kugadzirisa kusagadzikana kwemetabolism uye kusimudzira kugadzirwa kwecholesterol yakanaka, nemhedzisiro yekugadziriswa kwematunhu ehypertension uye kudzivirira njodzi dzemoyo.

Hesperidin Benefits

Sezvo zviri nyore kunzwisisa, hesperidin inogona kuva mushonga unobatsira wekudzivirira uye kubata kumwe kusagadzikana kune chekuita nekutenderera kwemakumbo ezasi, kuwedzera kwemidziyo uye peripheral microcirculation..

Vanotambura venous insufficiency nezviratidzo zvakasiyana-siyana zvinogona kubatsirwa nazvo:

• hemorrhoids: dambudziko rinonyanya kukurukurwa rinosanganisira mukati kana kunze vasodilation ne extroflexion kuzvimba uye kubuda ropa kunogona. Hesperidin inopesana neatony yemidziyo uye pamusoro pezvose inodzivirira kuoneka kwavo zvakare.
• varicose kana varicose tsinga: Zvishoma sehemorrhoids, varicose veins zvakare yakanyungudutswa tsinga, dambudziko rinowanzobata pasi pemigumo, rinowanzowedzerwa ne venous stasis.

Hesperidin inonongedza tsinga, inosimudzira kutenderera, inodzivirira zvinobvira zvakakomba pathologies senge phlebitis.

• fragile capillary: Chirwere chinowanzoongororwa chete nekuda kwekunakidza kwaro, asi izvo zvinogona kuratidza zvakanyanya kuoma pathologies, inozviratidza seyakawanda kana zvishoma yakawanda bluish web inogona kuonekwa pamakumbo, asiwo pachiso.

Hesperidin inobatsira kusimbisa capillary madziro, inodzivirira kuumbwa kwemavanga uye inokurudzira kuvandudzwa kwemanetwork.

• cholesterolemia: rubatsiro rwakajeka rwakaonekwa munyaya yekuwedzera kwecholesterol yakazara nezvidzidzo zvaitarisira kutora hesperidin kweinenge 4 mavhiki, nechido chokugadzirwa kwecholesterol yakanaka, nokudaro ichideredza iyo yeLDL.

Nzira yekutora hesperidin

Zvinokwanisika kuwana hesperidin semushonga wega kana mukuwirirana nemamwe misimboti anoshanda ari mumutsvairo webhucha, muzambiringa mutsvuku, chestnut yebhiza, sweet clover uye gotu kola..

Nhamba yezuva nezuva yehesperidin inokurudzirwa 500 mg zuva nezuva. Iko hakuna contraindications kana mhedzisiroSeyero yekudzivirira, kushandiswa kwayo hakukurudzirwi panguva yekuzvitakura uye lactation.

Quercetin uye COVID-19

NezveCCIDID-19, quercetin yakaratidzwa kuita pa3CLpro, imwe yemapuroteni akakosha ekudzokorodza kwehutachiona hweSARS-Cov-2, ichiikanganisa uye pamwe ichitadzisa kudzokororwa kwayo.

Maonero angu

Kufarira kwevatsvakurudzi muquercetin uye, kunyanya, mune mamwe maflavonoids ari mumichero nemiriwo zviri pachena.Tinoona zvakare zvakajeka kuti zvidzidzo zvakajaira kunwa zvakanyanya kwemichero nemiriwo zvinowanzovimbisa kuderedzwa kwengozi kuita mamwe marudzi egomarara. Zvidzidzo mumachubhu ekuedzwa uye mhando dzemhuka zvinoratidza mamwe maanticancer emhando yeflavonoids (quercetin uye mamwe maflavonoids anodzivirira kenza kukura muzamu, colon, prostate, ovarian, endometrial, uye kenza yemapapu), asi ipfungwa yemunyori kuti kushomeka kwakafanana. mhedzisiro muvanhu ingangove yakabatana nenyaya yekuti quercetin inoshanda seyakazara mune yakaoma synergistic mhedzisiro inosanganisira akawanda (mazana? zviuru?) muhuwandu hwakawanda, kuitira kuti tive nechokwadi chekugara kwakakwirira muropa pasinei nehafu yehupenyu hwehupenyu hwezvinhu izvi.

Mumashoko akareruka, ndinotenda kuti kiyi yechokwadi chekudzivirira chiri mukushandiswa kwezuva nezuva kwezvibereko nemiriwo, panzvimbo pekuedza myopic kubereka migumisiro yavo mufomu yepiritsi.

Maitiro ekuita

Quercetin yakagara ichikwezva kufarira kwevaongorori nekuda kwekugona kwayo kuita sea natural inhibitor yema enzymes akawanda evanhu. Enzymes zvinhu (zvizhinji zveprotein nature) zvinokwanisa kusimudzira kukurumidza kwemakemikari kuita, dzimwe nguva kumhanyisa zvinoshamisa (zvekuti kana enzyme isipo kuita kwacho kwaizotora nguva yakareba zvekuti yaisazoonekwa sezviri kuitika) .

Nokudaro, quercetin inokwanisa  lock kana kudzikisira kuita uku, kusanganisira:

• kushandurwa kwe testosterone kune dihydrotestosterone
• kushandurwa kwe androgens kune estrogens
• synthesis ye leukotrienes uye arachidonic acid (inobatanidzwa muzviitiko zvinoputika)
• nzira dzakasiyana dzebiochemical dzine chekuita nekuwedzera kwesero.

Nekuda kweichi chivakwa chekupedzisira, inowanzova pakati pekutarisisa kana zvasvika pakutsvagisa cancer, ndiko kuti, kutsvaga kwemamorekuru anogona kuve. zvinogona antitumor zvinodhaka.

Iyo bioavailability yequercetin muvanhu, ndiko kuti, mari yakambodyiwa inopinda muropa, kazhinji yakaderera uye inoshanduka zvakanyanya pane zvakanakisa (0-50%).

Zvikonzero zvekusawirirana mumigumisiro pakati pe test tube / zvisikwa hazvisi nguva dzose zvakajeka, asi pakati pekufungidzira kwakanyanya, musiyano webioavailability pakati pechimiro chekudya uye chimiro chinowanzoshandiswa pakugadzirira kwekuwedzera (aglycone, apo muzvokudya in use) inomira pachena. glycoside form).

Inobva yabviswa nokukurumidza, zvakadai kuti hafu yeupenyu (nguva inotora kuona hafu yehuwandu muropa) inongova maawa 1-2 (zvisinei nokuti iyo inobva kune chikafu kana kuwedzera). Zvakare nekuda kwechikonzero ichi, vaongorori vazhinji vanonyatsogutsikana kuti kudyiwa kwechikafu hakutenderi chinhu kuratidza mhedzisiro inocherechedzwa mu vitro (rabhoritari).

Quercetin Side Effects

Quercetin inoonekwa seyakachengeteka kudyiwa kwechikafu, zvekuti muna 2010 US FDA yakazviona seyakachengetedzeka kunyangwe muchimiro chekuwedzera kusvika kumadhora mazana mashanu pasevhisi.

Panyaya yemadosi aripo muzvekuwedzera, kuongororwa kunonyanya kuoma (uye nekuti nguva zhinji aya magadzirirwo akagadzirirwa kudyiwa zuva nezuva uye kwete apo neapo sepakudya) uye pane huwandu husina kukwana hwebasa rekuongorora chetoxicological. kuchengetedzwa kwemorekuru) kutora mhedziso dzechokwadi.

Mamwe masosi anoshuma budiriro inogona kuitika ye kutemwa nemusoro uye zvirwere zvomudumbu.

Kazhinji, kunyangwe vamwe vanyori vachisimudza zvinonetsa (semuenzaniso zvine chekuita nenjodzi yekusimudzira mamota anotsamira pahomoni), quercetin ichiri kunzi yakachengeteka pamiyero inowanzotarisirwa kuwedzerwa muvakuru.

Contraindication

Nekuda kweiyo precautionary musimboti (hapana humbowo hwengozi kana kuchengeteka) zvinokurudzirwa kudzivirira kutora ma supplements kana:

• vakadzi vane pamuviri uye vanoyamwisa,
• vana nevachiri kuyaruka.

Nekudaro, iyo contraindicated kune varwere vane inozivikanwa itsvo matambudziko.

Kudyidzana kwezvinodhaka

Quercetin inhibitor ine simba ye cytochrome P3 enzymes CYP4A2 uye CYP6D450, imwe yenzira dzinonyanya kukosha mumetabolism yemishonga yakawanda. Izvi zvinoreva kuti mishonga inoshandisa nzira iyi kuti ibviswe inogona kutambura kubva pakugona kwemhedzisiro, ine njodzi huru yekusangana nemhedzisiro. Nemamwe mashoko, Zvinokurudzirwa KUSATI kutora quercetin-based supplements kana iwe ukatora mishonga yakagadziriswa nema enzymes aya.s (inowanzo kuratidzwa mupakeji yekuisa, chaizvo nekuti yakajairika).

Kune dzimwe dziviriro dzinofanirwa kutorwa maererano nemakirasi chaiwo emishonga, semuenzaniso:

• Mishonga yeBP yeBP (sezvo vamwe vanyori vachiratidza kuti inogona kunge iri hypotensive effect, kusangana nemishonga inotorwa nechinangwa chimwe chete kunogona kukonzera kuwedzera kwemhedzisiro),
• mishonga yechirwere cheshuga (idem).