La quercetin yana cikin rukuni na abubuwan polyphenolic da aka sani da flavonoids.

An gano Flavonoids daga masanin kimiyya dan kasar Hungary Albert Szent-Györgyi, wanda ya gano bitamin C (ya lashe kyautar Nobel ta likitanci da ilimin lissafi a 1937), wanda ya lura cewa. flavonoids suna da tasirin synergistic tare da bitamin C.

Quercetin kwayar halitta ce ta polyphenolic da aka samar ta hanyar sarrafa wasu tsire-tsire irin su doki chestnut, calendula, hawthorn, chamomile, St. John's wort da ginkgo biloba, amma har da 'ya'yan itatuwa, kayan lambu, ganye, tsaba da hatsi.

Ana danganta kaddarorin antioxidants da anticancer, da sauransu.

A ina za mu iya samun quercetin?

An rarraba Quercetin a cikin masarautar shuka: mun same shi a cikin 'ya'yan itatuwa, peels da rinds na apples and albasa, koko, jajayen 'ya'yan itatuwa da broccoli. Musamman albarkatu masu wadata sune 'ya'yan itatuwa citrus, man zaitun, albasa, jan giya, koren shayi, da kuma St. John's wort.

Ana fitar da quercetin da aka saba amfani da shi a cikin kayan abinci daga cikin buds na shagon japonica (wani tsiro na iyali Fabaceae - Legumes) kuma aka sani da Jafananci Robinia, Jafananci acacia ko itacen pagoda. Shuka, na asalin Asiya (China da Koriya), yana tsiro a cikin in mun gwada da dumi da yanayin zafi sannan kuma tana yaduwa a yankunan da ke da matsanancin yanayi na Turai.

Tun da shagon japonica yana da wadata sosai a cikin quercetin, yana yiwuwa a sami tsantsa mai tsafta a zahiri. Quercetin shine mafi girma ana amfani da shi don cututtuka na rayuwa da kumburi kuma babban aikin da aka danganta da shi shine antioxidant.

A gaskiya ma, yana taimakawa wajen rage samuwar radicals da abubuwan da ke haifar da kumburi, yana tabbatar da zama abokin tarayya mai mahimmanci ga lafiyarmu. Bugu da ƙari, ana danganta kaddarorin zuwa gare ta vasoactive tun yana ƙara juriya na capillaries kuma yana daidaita yanayin su.

Tasirin Quercetin

Quercetin yana da ayyuka masu zuwa:

• anti-mai kumburi,
• antiestrogen,
• rage samuwar endometrial nama,
• raguwa mai yawa a cikin hawan jini na systolic a cikin marasa lafiya na kan iyaka, musamman idan suna da kiba,
• antiatherosclerotic ta hanyar hana LDL oxidation da sakamakon lalacewar endothelial arterial,
• kariya ta zuciya,
• antiviral,
• immunomodulator,
• antiallergic,
• gastroprotective.

Yaya ake shan quercetin?

Quercetin yana shiga cikin hanji kuma ana rarraba metabolites ta hanta zuwa kyallen jikin daban-daban na jiki. A cikin plasma yana ɗaure zuwa albumin. The Ana kaiwa ga kololuwar plasma kusan awanni 7 bayan an sha kuma kawar da rabin rayuwar shine kusan sa'o'i 25. Samuwar quercetin da baki ba shi da tabbas: a zahiri, ya bayyana cewa quercetin ya fi kyau kuma ya fi dacewa da shi a cikin hanji idan an sha shi tare da mai kamar matsakaicin sarkar triglycerides. Abin da ya sa yana da mahimmanci cewa abubuwan da ake amfani da su sun ƙunshi abubuwa masu lipid kuma ana ɗaukar su a cikin cikakken ciki.

Ganin cewa binciken kimiyya ya nuna cewa yawan shan flavonoids yana rage haɗarin cututtukan zuciya da jijiyoyin jini kuma quercetin ya fi kasancewa a cikin abincinmu, yana da kyau mu ci 'ya'yan itatuwa da kayan marmari a kullum.

Idan a zahiri ba a ɗauki isasshen adadin polyphenols ba ko kuma musamman yanayin kiwon lafiya wanda ya zama dole don ɗaukar su da yawa, ana iya amfani da amfani da kayan abinci na abinci muddin suna ɗauke da daidaitattun abubuwan da suka dace, waɗanda ke da alaƙa da masu haɓaka sha. wannan ni'imar assimilation.

A cikin ƙarin, matsakaicin yawan abincin yau da kullun da Ma'aikatar Lafiya ta yarda shine 200 MG kowace rana amma, godiya ga amfani da wasu samfurori na abubuwan da ke inganta shayarwa, ƙananan adadin zai isa.

Menene tushen asali na quercetin?

Quercetin yana daya daga cikin mafi yawan flavonoids na abinci, don haka matsakaicin abincin yau da kullun ta hanyar abinci na yau da kullun an kiyasta kusan 25-50 milligrams.

Wasu daga cikin abinci/abinci mafi girma a cikin quercetin sun haɗa da:

• capers (dangane da nauyi, shi ne shuka wanda ya ƙunshi mafi yawan, 234 MG da 100 g na raw buds),
• buckwheat,
• farin / ja inabi
• jan giya (a gaskiya, a cikin inabi, wannan yana haɗawa a cikin nau'in fari da ja, amma dangane da ruwan inabi, ya fi girma fiye da kowa a cikin jan giya ta hanyar tsarin canji)
• Jan albasa,
• Koren shayi,
• blueberry,
• Apple,
• propolis,
• seleri,
• radish,
• kabeji.
• apples,
• inabi,
• kofi,
• berries,
• broccoli,
• 'ya'yan itatuwa citric,
• da cherries.

Yawancin flavonoids a cikin abincin sun fito ne daga quercetin.

Mafi bioavailable quercetin kuma saboda haka mafi kyawun assimilated shine na fata apple.

Kar a jefar da harsashi

Ya kamata a tuna cewa a cikin ja albasarta mafi girma na quercetin ana samun su ba kawai a cikin ɓangaren da ke kusa da tushen ba, ɓangaren shuka tare da mafi girma, amma har ma a cikin zobba na waje. Wannan sabon abu ne quite na kowa a cikin yanayi da kuma shi ne mai mulkin da bai kamata a manta a cikin kitchen, musamman a lokacin da muka yi laifi rabu da mu da peels da kuma m yadudduka na kayan lambu da 'ya'yan itatuwa ma sauƙi, manta da cewa suna wakiltar musamman m tushen bioactive abubuwa.

El Cin abinci mai kitse tare da tushen abinci na quercetin yana da alama yana iya ƙara sha tasiri, wanda a cikin kanta yana da iyaka. Hakanan kasancewar carbohydrates, godiya ga haɓakar motsin gastrointestinal da abubuwan haifuwa a cikin hanji, na iya samun sakamako mai kyau a wannan batun.

Ta yaya quercetin ke shafar tsarin rigakafi?

Wannan abu yana da antiviral Properties goyon bayan daban-daban karatu a cikin dabbobi model, amma rashin alheri har yau ba mu san ainihin sakamako da kuma mataki na wannan abu a kan tsarin rigakafi.

A ƙarshe, wasu theories yi imani da cewa zai iya zama da amfani kawai a karkashin wasu yanayi na matsananci psychophysical danniya.

Menene quercetin da ake amfani dashi?

Daga cikin alamomin da aka fi amfani da shi har da maganin kumburin ciki da kuma maganin antioxidant, wanda ya haifar da amfani da shi a wurare da yawa na likitanci da kuma dalilai daban-daban:

• goyon bayan tsarin rigakafi,
• rage kumburi,
• ingancin antitumor (ban da rigakafi),
• sarrafa sukarin jini,
• goyon bayan wasan kwaikwayo
• rigakafin cututtuka na zuciya da jijiyoyin jini.

Ƙananan alamomi sun haɗa da:

• amosanin gabbai,
• interstitial cystitis,
• prostatitis.

An yi nazarin Quercetin a cikin bincike na asali (in vitro, watau, a cikin bututun gwaji ko iyaka a cikin nau'ikan dabbobi) da kuma a cikin ƙananan gwaje-gwaje na asibiti (a cikin mutane), amma yayin da yawancin abubuwan da aka inganta don maganin ciwon daji da sauran cututtuka akwai a halin yanzu. rashin isassun shaida na isassun inganci don nuna ainihin inganci mai iya aunawa.

Ta yaya kuma yaushe za ku ɗauki quercetin idan kuna yin wasanni?

Kariyar Quercetin na iya ɗan goyan baya juriya motsa jiki yi.

Shin quercetin yana da aikin antioxidant?

Kyakkyawan aikin shine saboda aikin antioxidant wanda ke taimakawa yaki da radicals kyauta.

anti-mai kumburi mataki

A cewar wasu nazarin, quercetin na iya taimakawa wajen magance kumburi, amma rashin alheri, har ma a wannan yanayin, shaidar tana iyakance a yanzu.

Shin zai iya samun amfani ga prostatitis?

A wasu nazarin, quercetin ya magance kumburin prostate.

Zai iya tallafawa tsarin zuciya da jijiyoyin jini?

Quercetin na iya zama taimako ga hawan jini na al'ada kuma yana da wasu fa'idodi ga lafiyar zuciya da jijiyoyin jini.

Yaya da kuma lokacin da za a dauki quercetin?

Adadin da aka nuna a wasu nazarin ya bambanta tsakanin 100 zuwa 1.000 MG kowace rana.

Menene contraindications da sakamako masu illa na quercetin?

Ganin rashin karatu, ana bada shawarar kada a sha quercetin a lokacin daukar ciki da kuma lactation.

Yana da amfani koyaushe don tuntuɓar likitan ku kafin shan quercetin don zaɓar magani mafi dacewa. Kada a wuce adadin da aka ba da shawarar.

Hesperidin da quercetin

La hesperidin wani flavonoids ne samu yafi a cikin citrus. Halaye da tasirin antioxidant, ana danganta kaddarorin vasoprotective zuwa gare shi saboda aikin sa akan collagen da nama mai haɗawa, don haka ba sabon abu bane samun kari akan kasuwa wanda ke haɗa shi da quercetin.

Hesperidin, kaddarorin da fa'idodi

Hesperidin magani ne na halitta da amfani ga microcirculation da kuma cututtukan da ke da alaƙa da tsarin jijiyoyin jini. Basir, varicose veins, amma kuma yawan cholesterol na iya amfana da shi sosai.

Faduwa, kakar citrus, ruwan 'ya'yan itace, bitamin C ... da kuma tunanin cewa akwai wani ɓangare na citrus wanda ba mu la'akari da shi ba, saboda yana da fata, mai ɗaci, mai arziki a cikin mai: da fur. Kuma shi ne daidai a cikin harsashi inda sami daya daga cikin mafi amfani flavonoids tsakanin antioxidant kari, hesperidin.

Hesperidin yana samuwa a cikin fata da kuma farar bawo a ƙasan kwasfa na 'ya'yan itatuwa citrus. Mafi ban sha'awa bangaren hesperidin a cikin Pharmaceutical da kuma ganye filin ne na yau da kullunsaboda da vasoprotective Properties.

Hesperidin Properties

An bayyana kaddarorin hesperidin a cikin microcirculation, a cikin jini da kuma bayan. Bari mu ga mafi kyawun ayyukan da wannan flavonoids ke yi:

• capillarotropic: sautin capillaries, yana hana haɓakawar su kuma yana taimakawa wajen ƙarfafawa da haɓaka tsarin capillary.
• vasoprotective: yana aiwatar da toning da aikin kariya akan tasoshin jini, yana hana aton su, stimulating venous wurare dabam dabam da kuma yin aikin anti-mai kumburi.
• hypocholesterolemic: yana da ikon gyara rikice-rikice na rayuwa da haɓaka samar da ƙwayar cholesterol mai kyau, tare da sakamakon gyare-gyaren jihohin hauhawar jini da rigakafin haɗarin cututtukan zuciya.

Amfanin Hesperidin

Kamar yadda yake da sauƙin fahimta, hesperidin na iya zama magani mai amfani don hanawa da kuma bi da wasu cututtuka masu alaka da zagayawa na ƙananan gaɓoɓi, dilation na tasoshin da microcirculation na gefe..

Wanene ya sha wahala rashin isasshen jini tare da bayyanar cututtuka daban-daban na iya amfana da shi:

• basur: Matsalar da aka tattauna sosai da ta haɗa da vasodilation na ciki ko na waje tare da kumburi extroflexion da yiwuwar zubar jini. Hesperidin yana magance atony na tasoshin kuma sama da duka yana hana bayyanar su.
• varicose ko varicose veins: Kamar ciwon basir, varicose veins suma su ne fashe-fashe, matsalar da ta kan yi wa kasan gaba, yawan tabarbarewar venous.

Hesperidin yana inganta jijiyoyi, yana inganta wurare dabam dabam. Yana hana yiwuwar tsanani pathologies kamar phlebitis.

• m capillary: rashin lafiya sau da yawa ana kimantawa kawai don tasirinsa na ado, amma wanda zai iya nuna alamun cututtuka masu tsanani, yana bayyana kansa a matsayin mafi ko žasa mai zurfi na yanar gizo wanda zai iya bayyana akan kafafu, amma kuma a kan fuska.

Hesperidin yana taimakawa wajen ƙarfafa ganuwar capillary. yana hana samuwar raunuka kuma yana ƙarfafa ci gaban cibiyoyin sadarwa.

• cholesterolemia: an ga wani fa'ida mai fa'ida a cikin yanayin karuwar adadin cholesterol ta hanyar binciken da aka yi tsammani shan hesperidin na akalla makonni 4, tare da buƙatar samar da cholesterol mai kyau, saboda haka rage na LDL.

Yadda ake shan hesperidin

Yana yiwuwa a sami hesperidin a matsayin magani kawai ko A cikin aiki tare da wasu ƙa'idodi masu aiki waɗanda ke ƙunshe a cikin tsintsiya madaurinki ɗaya, jan itacen inabi, chestnut doki, clover mai zaki da gotu kola..

Matsakaicin shawarar yau da kullun na hesperidin shine 500 MG kowace rana. Babu contraindications ko sakamako masu illaA matsayin ma'auni na rigakafi, ba a ba da shawarar yin amfani da shi ba a lokacin daukar ciki da lactation.

Quercetin da COVID-19

Game da COVID-19, an nuna quercetin yana aiki akan 3CLpro, ɗaya daga cikin mahimman sunadaran don kwafin ƙwayar cuta ta SARS-Cov-2, yana lalata shi kuma yana iya hana kwafinsa.

Ra'ayina

Sha'awar masu bincike game da quercetin da, gabaɗaya, a cikin sauran flavonoids da ke cikin 'ya'yan itatuwa da kayan marmari a bayyane yake.Haka kuma muna gani a fili cewa abubuwan da suka saba da yawan 'ya'yan itatuwa da kayan marmari suna ba da garantin rage haɗarin kamuwa da cuta. bunkasa wasu nau'ikan ciwon daji. Nazarin da aka yi a cikin bututun gwaji da samfuran dabbobi sun nuna wasu kaddarorin anticancer na flavonoids (quercetin da sauran flavonoids suna hana ci gaban ƙwayar cutar kansa a cikin nono, hanji, prostate, ovarian, endometrial, da cututtukan huhu), amma ra'ayin marubucin ne cewa rashin daidaitaccen bayyanar. sakamako a cikin mutane tabbas yana da alaƙa da gaskiyar cewa quercetin yana aiki gabaɗaya a cikin hadaddun tasirin synergistic da ke tattare da yawa (daruruwan? dubbai?) Sauran abubuwa masu aiki da abubuwa waɗanda ke cikin 'ya'yan itatuwa da kayan marmari, waɗanda zasu iya nuna tasirin gaske kawai lokacin cinyewa akai-akai kuma a cikin adadi mai yawa, don tabbatar da ci gaba mai yawa a cikin jini duk da ɗan gajeren rabin rayuwar waɗannan abubuwa.

A cikin kalmomi masu sauƙi, na yi imani cewa mabuɗin sakamako na rigakafi na gaske shine a cikin cin abinci na yau da kullum na 'ya'yan itatuwa da kayan marmari, maimakon a cikin ƙoƙari na myopic na sake haifar da tasirin su a cikin nau'in kwamfutar hannu.

Ayyukan aiki

Quercetin ya dade yana jawo sha'awar masu bincike don ikonsa na yin aiki azaman mai na halitta inhibitors na mutane da yawa enzymes. Enzymes abubuwa ne (gaba ɗaya na nau'in furotin) waɗanda ke da ikon haɓaka saurin amsawar sinadarai, wani lokacin kuma suna hanzarta shi sosai (ta yadda idan babu enzyme ɗin zai ɗauki lokaci mai tsawo har ma ba za a ɗauka yana ci gaba ba). .

Saboda haka, quercetin yana iya  kulle ko rage waɗannan halayen, gami da:

• canza testosterone zuwa dihydrotestosterone
• canza androgens zuwa estrogens
• kira na leukotrienes da arachidonic acid (wanda ke cikin abubuwan da ke haifar da kumburi)
• hanyoyi daban-daban na biochemical da ke da alaƙa da yaduwar kwayar halitta.

Godiya ga wannan dukiya ta ƙarshe, sau da yawa ita ce cibiyar kulawa idan aka zo ga binciken ciwon daji, wato, binciken kwayoyin da za su iya zama. m antitumor kwayoyi.

Halin da ake samu na quercetin a cikin mutane, wato, adadin da da zarar an sha yana shiga cikin jini, gabaɗaya ya yi ƙasa da ƙasa kuma yana canzawa sosai (0-50%).

Dalilan rashin daidaituwa a cikin tasirin da ke tsakanin bututun gwajin / kwayoyin halitta ba koyaushe bane bayyananne, amma a cikin mafi yawan ra'ayoyin da aka yarda da su, bambancin yanayin rayuwa tsakanin nau'in abinci da nau'in da aka saba amfani da shi don shirye-shiryen kari (aglycone, yayin da yake cikin abinci yana cikin abinci). a cikin amfani) ya fito waje. glycoside form).

Sa'an nan kuma an kawar da shi da sauri, irin wannan rabin rayuwa (lokacin da ake ɗauka don ganin raguwar maida hankali a cikin jini) shine kawai 1-2 hours (ko da kuwa ko tushen abinci ne ko kari). Hakanan saboda wannan dalili, masu bincike da yawa sun tabbata a zahiri cewa cin abinci baya barin abu ya nuna tasirin da aka lura a cikin vitro (laboratory).

Quercetin Side Effects

Quercetin ana ɗaukarsa da aminci ga cin abinci, ta yadda a cikin 2010 FDA ta Amurka ta amince da shi a matsayin mai lafiya ko da a cikin nau'in ƙari har zuwa allurai na milligrams 500 a kowace hidima.

Game da allurai da ke cikin abubuwan kari, kimantawa ya fi rikitarwa (kuma saboda sau da yawa waɗannan nau'ikan tsari ne da aka tsara don ci yau da kullun ba lokaci-lokaci ba kamar a cikin abinci) kuma babu isasshen adadin aikin bincike mai guba (watau mai da hankali kan aminci na kwayoyin) don zana tabbataccen ƙarshe.

Wasu kafofin bayar da rahoton yiwuwar ci gaban ciwon kai da ciwon ciki.

Gabaɗaya, ko da yake wasu mawallafa sun tada damuwa (misali dangane da yiwuwar haɓakar ciwace-ciwacen da ke dogara da hormone), quercetin har yanzu ana ɗaukarsa lafiya a cikin allurai da ake sa ran samun kari a cikin manya.

Contraindications

Saboda ka'idar yin taka tsantsan (babu wata shaida na haɗari ko aminci) ana ba da shawarar a guji shan kari idan akwai:

• mata masu ciki da masu shayarwa,
• yara da matasa.

Duk da haka, an hana shi a cikin marasa lafiya tare da sanannun matsalolin koda.

hulɗar miyagun ƙwayoyi

Quercetin shine mai hanawa mai ƙarfi na cytochrome P3 enzymes CYP4A2 da CYP6D450, ɗayan mahimman hanyoyin da ke cikin metabolism na magunguna da yawa. Wannan yana nufin cewa magungunan da ke amfani da wannan hanyar da za a kawar da su na iya sha wahala daga tasirin tasiri, tare da babban haɗarin fuskantar illa. Watau, Ana ba da shawarar KADA ku ɗauki abubuwan da suka dogara da quercetin idan kun ɗauki magunguna waɗanda waɗannan enzymes suka daidaitas (yawanci ana yin alama a cikin abin da aka saka, daidai saboda suna da yawa).

Akwai wasu matakan kiyayewa waɗanda dole ne a ɗauka game da takamaiman nau'ikan magunguna, misali:

• magungunan hawan jini (tunda wasu marubutan suna ba da shawarar yiwuwar tasirin hypotensive, haɗin gwiwa tare da magungunan da aka sha don wannan dalili na iya haifar da haɓakar tasirin).
• magunguna don ciwon sukari (idem).